It is generally safe for people to vacuum confetti, as long as they take the necessary precautions.
When vacuuming confetti, it's important to use a vacuum that is appropriate for the type of flooring you have, such as a vacuum with a hardwood floor attachment for hardwood floors. It's also important to be gentle when vacuuming to avoid damaging the flooring or pushing the confetti deeper into the carpet fibers.
If the confetti is made of paper, it's a good idea to empty the vacuum's dustbin or bag frequently to prevent it from becoming too full and affecting the vacuum's suction power. For larger pieces of confetti, you can also use a broom and dustpan to sweep them up.
However, if the confetti is made of metallic materials or other materials that could damage your vacuum, it's best to avoid vacuuming it up altogether. Instead, use a broom and dustpan or a handheld vacuum to clean it up.
In any case, it's always a good idea to check the manufacturer's instructions for your vacuum cleaner to make sure that it is safe to use for cleaning up confetti.